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It’s an opioid medication which is sold under the brand name of OxyContin. It is used for treating to eradicate the pain . This medication is generally taken orally and is available in immediate release and controlled release formulations. If the person is suffering from nausea then doctors prefer to treat nausea first then give them the medication of OXYCODONE. It was derived from thebaine in Germany in 1917. It’s international and other brand name is as follows Oxanest/ oxyIR. There is also an extended release formulations indicated for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.
OXYCODONE acts directly on a number of tissues not related to its analgesic effect. These tissues include the respiratory centre in the brain stem, the cough centre in the brain stem, muscles of the pupil, endocrine system and immune system.
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Under the conditions of inflammation or hyperalgesia, opioid receptors in the heart , lungs, liver , gastrointestinal tract. OXYCODONE and it’s active metabolites can selectively bind to the mu opioid receptors in central nervous system and periphery and induce a G protein coupled receptor signalling pathway.
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